Review
Bergenia crassifolia (L.) Fritsch – Pharmacology and phytochemistry
Abstract
Purpose
Bergenia crassifolia (L.) Fritsch, a species in the Bergenia genus belongs to the family Saxifragaceae,
is valuated for its medicinal application. The review focuses on the
medicinal uses, phytochemistry, and the biological activities of B. crassifolia to explore its benefits and potential uses.
Methods
In this review, we summarized data, published in Russia and in other countries related to B. crassifolia.
Results
Rhizomes
and leaves of this plant are in use as traditional remedies for the
treatment of different disorders in the folk medicine systems of Russia
and Asia. The plant is a potential source of tannins, benzanoids,
flavonoids, polysaccharides and other active compounds. Due to the
presence of a multitude of bioactives, a wide array of pharmacological
activities have been ascribed to different parts of this herb and
individual compounds, which include adaptogenic, antiinflammatory,
antihypertensive, antimicrobial, antioxidant, antiobesity, antitussive,
cerebro-protective, hepatoprotective, immunomodulating, and diuretic.
Conclusion
The review highlights the potential of B. crassifolia for further development of herbal medicines on its base.
Graphical abstract
Keywords
- Bergenia crassifolia;
- Pharmacological effects;
- Active compounds
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+7 812 3225605; fax: +7 812 3225605.
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