Invited mini review
Plantamajoside — A current review
Highlights
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- The distribution of plantamajoside in plants and in different plant parts is discussed.
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- The biosynthesis and chemical synthesis of plantamajoside is also covered.
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- The properties of plantamajoside as a chemotaxonomical biomarker and protective properties in plants is discussed.
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- An exhaustive description of the bioactivities and potential of plantamajoside as a new drug compound is highlighted.
Abstract
Plantamajoside
is a bioactive caffeic acid derivative, a dihydroxyphenethyl glucoside
in the group of polyphenolic compounds. It is one of the principal
caffeic acid glycoside in the Plantago Digitalis, Hemiphragma, Lagotis, Picrorhiza, Rehmannia, Veronica, Wulfeniopsis and Wulfenia genera within the Plantaginaceae family. This compound is also present in the genera Aeschynanthus and Chirita of the Gesneriaceae family and the genus Boschniakia
of the Orobanchaceae family. Plantamajoside is present in the greatest
concentrations in roots of young plants, but it is also found in seeds,
flower stalks, stems, leaves, in vivo cultivated plant cells
and transgenic root cultures. Plantamajoside is used as a biomarker in
chemotaxonomical studies, and is a compound with numerous biological
applications and considerable pharmacological potential. It is a
protective agent against ultra-violet light in plants and acts as
antioxidant agent with very low toxicity. In addition, plantamajoside
can also be industrially synthesized. This review aims to give an
overview of plantamajoside in various plantago species as well as its
potential as a biomarker and as a new drug compound.
Graphical abstract
Keywords
- Bioactivity;
- Caffeic acid derivative;
- Chemotaxonomy;
- Phenylpropanoid metabolism;
- Plantago
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Copyright © 2015 Phytochemical Society of Europe. Published by Elsevier B.V. All rights reserved.
