Abstract
Purpose.
This study evaluates both scopes of 4DryField PH, certified for
adhesion prevention and hemostasis, in patients undergoing surgery for
various and severe gynecological disorders. Methods. This is a
two-institutional study. Adhesion prevention efficacy was evaluated
using video documentation of first-look laparoscopies (FLL) and
second-look laparoscopies (SLL); other patient data were analyzed
retrospectively. Twenty patients with various disorders were evaluated, 4
assigned to a uterus pathology, 10 to endometriosis, and 6 to an
adhesion disease group. Nine patients received 4DryField primarily for
hemostasis and 11 solely for adhesion prevention. Nineteen patients had
SLL after 5 to 12 weeks and one after 13 months. Results. At FLL
with 4DryField, immediate hemostasis could be achieved in diffuse
bleeding. At SLL, effective adhesion prevention was observed in 18 of
all 20 women, with only 2 revealing major adhesions. In particular, only
1 of the 6 women with adhesion disease as predominant disorder showed
major adhesions at SLL. Conclusions. Modified polysaccharide
4DryField is not only effective in diffuse bleeding. In this cohort with
extensive surgery for various gynecological pathologies, 4DryField
showed effective adhesion prevention as confirmed at SLL, too. Its use
as premixed gel is a convenient variant for treatment of large
peritoneal wounds.
4DryField® PH
PROVIDES HEMOSTASIS – PREVENTS ADHESIONS
4DryField® PH is an innovative product concerning
Hemostasis plus
Adhesions prevention
for several surgical fields of application. 4DryField® PH is an
absorbable starch powder for application to surgical wounds by
physicians or medical-technical specialists.
4DryField® PH consists of hydrophilic microparticles produced from
purified starch of plant-based origin. 4DryField® PH is ready-to-use and
can be applied directly to bleeding or oozing surfaces. The free
flowing properties of 4DryField® PH permit simple and safe application
during surgical interventions.
4DryField® PH absorbs within seconds a multiple of its own mass of water, which induces two effects:
Hemostasis plus
Adhesion prevention combined in
one medical device.
Hemostasis: Rapid water absorption transforms the
wound blood into the patient’s own “fibrin glue” formatting a highly
efficient coagulum to the wound.
Adhesions prevention: In presence of water
4DryField® PH particles form a gel, which acts as a temporary mechanical
barrier preventing adhesion formation.
4DryField® PH does
not contain any components of animal or human origin. It is biocompatible, free of pyrogens and allergens.
Side effects have not been reported.
