a
Department of Global Public Health and Primary Care and Centre for Pharmacy, University of Bergen, Bergen
b Pharmacoepidemiology and Drug Safety Research Group, Department of Pharmacy, School of Pharmacy, University of Oslo, Oslo
c The Motherisk Program, Division of Clinical Pharmacology and Toxicology, The Hospital for Sick Children, Toronto
b Pharmacoepidemiology and Drug Safety Research Group, Department of Pharmacy, School of Pharmacy, University of Oslo, Oslo
c The Motherisk Program, Division of Clinical Pharmacology and Toxicology, The Hospital for Sick Children, Toronto
Abstract
Background: The
factors related to the treatment of nausea during pregnancy have not yet
been investigated in several countries simultaneously. The present
study aimed to describe differences in self-reported nausea during
pregnancy and the patterns of use for both conventional and herbal
medicines across countries. The factors related to nausea and its
treatment and the relationships between different self-reported
co-morbidities and nausea were also investigated. Methods: This
cross-sectional study used data collected by a web-based questionnaire
distributed between October 2011 and February 2012 in several countries
within five regions: Western, Northern, and Eastern Europe,
North America, and Australia. Women who were pregnant or had a child
less than one year old were eligible to participate. Results: A total of
9113 women were included in the study, whereof 6701 (73.5 %) had
experienced nausea during pregnancy. Among respondents with nausea,
conventional medicines were used by 1201 (17.9 %) women and herbal
medicines by 556 (8.3 %) women. The extent of self-reported nausea and
its treatment varied by country. Education, working status, and folic
acid use were significantly associated with the use of conventional
medicines against nausea. Respondents who had nausea also had a high
burden of co-morbidity. Conclusion: The prevalence of nausea was high
across all participating countries but its treatment varied, possibly
due to cultural differences and differences in attitudes towards
medicines. A high degree of co-morbidity was found among respondents
with nausea. © 2015 Heitmann et al.
Author keywords
Herbal medicine; Internet; Multinational; Nausea; Pharmacotherapy; Pregnancy
ISSN: 14712393
CODEN: BPCMBSource Type: Journal
Original language: English
DOI: 10.1186/s12884-015-0746-2Document Type: Article in Press
Publisher: BioMed Central Ltd.
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