Aloe vera-induced acute liver injury: A case report and literature review

Clin Res Hepatol Gastroenterol. 2016 Nov 14. pii: S2210-7401(16)30150-4. doi: 10.1016/j.clinre.2016.10.002. [Epub ahead of print]

Parlati L¹, Voican CS², Perlemuter K³, Perlemuter G⁴.

Author information

• ¹AP-HP, Hôpital Antoine-Béclère, Service d'Hépato-Gastroentérologie et Nutrition, DHU Hepatinov, 92140 Clamart, France; Université Paris-Sud, Faculté de Médecine Paris-Sud, 92140 Clamart, France.
• ²AP-HP, Hôpital Antoine-Béclère, Service d'Hépato-Gastroentérologie et Nutrition, DHU Hepatinov, 92140 Clamart, France; Université Paris-Sud, Faculté de Médecine Paris-Sud, 92140 Clamart, France; INSERM U996, IPSIT, Labex Lermit, 92140 Clamart, France.
• ³Centre Médical Luxembourg, 75005 Paris, France.
• ⁴AP-HP, Hôpital Antoine-Béclère, Service d'Hépato-Gastroentérologie et Nutrition, DHU Hepatinov, 92140 Clamart, France; Université Paris-Sud, Faculté de Médecine Paris-Sud, 92140 Clamart, France; INSERM U996, IPSIT, Labex Lermit, 92140 Clamart, France. Electronic address: gabriel.perlemuter@aphp.fr.

Abstract

Recent data suggest that herbal and dietary supplements are the second most common cause of liver injury. We herein report a case of acute liver injury in a 68-year old female caused by ingestion of Aloe vera. Upon discontinuation of the oral Aloe vera, liver function tests (LFT) returned to normal levels. Thus, it is crucial to consider the use of herbal products as causative agents of acute liver injury.